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BioCee coating technology is independent from the specific biological
system and pathway, applicable to most organisms and therefore it truly
represents a platform technology with broad applicability. It can improve and
extend the application of biotechnology in current operations and has the
exciting potential to bring the
benefit of biotechnology to new unconventional applications.
BioCee has identified three strategic areas of interest around which the
company is being developing in this order of priority:
- Biodesulfurization of petroleum and petroleum fractions
- Removal of phosphorus and other nutrients from agricultural wastewaster
- Bioactive coatings


Environmental regulations around the world, driven by the need to reduce
air pollution, are putting ever tighter limits on the sulfur content of liquid
transportation fuels at the same time as sweet, low-sulfur crude oil supplies
are increasingly replaced by sour, high-sulfur crude. This trend is driving the search for new, cost effective
desulfurization technologies. The current standard technology,
hydrodesulfurization (HDS), is operationally expensive because of high temperatures
and pressures, uses hydrogen whose price is tied to natural gas and is not
selective - especially for deep desulfurization - leading to loss to
hydrocarbons because of cracking. Biodesulfurization - which doesn't contribute to any further increase of
the carbon footprint of the stream being treated - has been regarded as a promising alternative or complement to
HDS. Not only are the microbial
catalysts used in BDS particularly successful in removing sulfur from the
compounds most difficult to treat with conventional hydrodesulfurization, the
technology also has the potential to significantly reduce energy consumption
and greenhouse gas emissions. Over the last 20
years, over $100 million has been
invested in the development of highly optimized microorganisms However, ultimately, the process did not
develop commercially because of issues related to mass transfer, loss of
biocatalyst and operational complexity. BioCee's technology promises to overcome
these barriers while taking advantage of the previous investments in the development
of the BDS microorganisms.

Phosphorus loading in agricultural waste water is among the leading
causes of eutrophization in bodies
of water. Run-off from the Mississippi water shed is a key cause of harmful
algal bloom in the Gulf of Mexico. These algal blooms lead to hypoxia in the
affected bodies of water and severe impact on the health of their ecosystems. The number of large scale algal blooms caused by anthropogenic
activity has been estimated to be worldwide over 400. This problem has also
important economic consequences as
commercial fishing and the tourism industry are negatively
impacted. Furthermore, phosphorus, a non renewable resource
and an essential nutrient for agricultural productivity, is wasted.
Phosphorus removal from waste water is well understood and commonly
done in highly effective manner in any municipal waste water treatment.
Unfortunately these waste water treatments are scarcely amenable to be applied
cost effectively to disperse and individually relatively small stream flows of
agricultural waste water. Phosphorus can effectively removed by biological
means and in the process polyphosphates are produced. Unlike the salts that
capture phosphorus in many waste water treatment plants, these polyphosphates
are suitable to be recycled as fertilizers. BioCee is devoping a new low cost
phosphorus removal system based on a novel application of a biocoating. The
biocoating embeds phosphorus fixing micro-organisms and is designed to be
suitable for deployment at the farm level, therefore allowing the capture of
nutrients where they can be recycled and before they reach any major body of
water.

The potential applications of bioactive coatings in a variety of
industries are very numerous. One that BioCee will purse is that of protective
coating for structures and material that need to be submerged in natural bodies
of water.
In these same natural bodies of water, there are
numerous example of naturally occurring films created by organisms that protect
themselves against predation or ecosystem encroachment by releasing toxins.
These toxins have no impact on a macroscopic scale but are highly effective in
protecting the host that releases them. BioCee technology allows to extend this
natural concept by embedding these micro-organisms in coatings which in turn
can be applied like a paint to the surface which are to be protected. This concept will provide an
environmentally benign alternative to current antifouling coatings and paints.
These use heavy metals and other chemicals which - as a consequences -are often
detected in consequential quantities in the environment.
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